Collagen fibres determine the crack morphology in articular cartilage
نویسندگان
چکیده
منابع مشابه
The Effect of Collagen Fibres on Permeability of Articular Cartilage
The proteoglycan meshwork is deemed to be the main source of resistance to fluid flow in articular cartilage. Maroudas (1968) showed that the decrease in proteoglycan volumetric fraction from the tidemark (bone-cartilage interface) to the articular surface corresponds to an increase in permeability from tidemark to surface, which is consistent with the well accepted “proteoglycan paradigm”. How...
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The extracellular framework and two-thirds of the dry mass of adult articular cartilage are polymeric collagen. Type II collagen is the principal molecular component in mammals, but collagens III, VI, IX, X, XI, XII and XIV all contribute to the mature matrix. In developing cartilage, the core fibrillar network is a cross-linked copolymer of collagens II, IX and XI. The functions of collagens I...
متن کاملCollagen of articular cartilage
The extracellular framework and two-thirds of the dry mass of adult articular cartilage are polymeric collagen. Type II collagen is the principal molecular component in mammals, but collagens III, VI, IX, X, XI, XII and XIV all contribute to the mature matrix. In developing cartilage, the core fibrillar network is a cross-linked copolymer of collagens II, IX and XI. The functions of collagens I...
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Adult articular cartilage by dry weight is two-thirds collagen. The collagen has a unique molecular phenotype. The nascent type II collagen fibril is a heteropolymer, with collagen IX molecules covalently linked to the surface and collagen XI forming the filamentous template of the fibril as a whole. The functions of collagens IX and XI in the heteropolymer are far from clear but, evidently, th...
متن کاملEffect of frequency on crack growth in articular cartilage
Cracks can occur in the articular cartilage surface due to the mechanical loading of the synovial joint, trauma or wear and tear. However, the propagation of such cracks under different frequencies of loading is unknown. The objective of this study was to determine the effect of frequency of loading on the growth of a pre-existing crack in cartilage specimens subjected to cyclic tensile strain....
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ژورنال
عنوان ژورنال: Acta Biomaterialia
سال: 2021
ISSN: 1742-7061
DOI: 10.1016/j.actbio.2021.03.031